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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '847ad5aeb545d1d81ed95be8b439ff526fdab5720b1dd405e8777e87339eedc9' 
  AND token = 'jy363uPVCiMmsHkUnHFjIDRs+RP5UTQvgCJkOA5gxFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}