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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8443d8b15c3587468696069728a601a1c523c151b799b3a9ff30e3a282d85f65' 
  AND token = 'Ee+3hKsadIoEV+5eMh71LFujZcUZy1BfpF31Fnda4u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}