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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b62f52de70644190a06e3c9133fa59b3afcc625bb5f1f06fe5aeb7d55f7bce54' 
  AND token = 'Yrtli+1aI2rltlss4h0sqTU2UDHFKrADg/0Vn00TyCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}