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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d322d72ff8e7d270c080cef4df21958060be7d4b4d88c83b9b52404ba18da16' 
  AND token = 'T2dXDkD1xPtBAKHtecYwQ+LUCh8qD/3F5txAoJd/yZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}