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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1dfad2607c1a6bec11afa3d461d89338490b955d6aefaaca5ec2d18e4a4cb1' 
  AND token = 'Z2WAzA8JDOdAQSagADEgED+cfAUMat2HMKOGzdfHyQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}