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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe10313ffcbbd0aef5f56fd51b03d47f31c0b212eca0d87409c5781e97c62c8' 
  AND token = 'GOYg5+nsNBDbBhYJN0/bRgIQBw5seDGfT36xbRhegTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}