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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065d7139d0033c809894cb6d75879b0578b648e0e645d591e2e975d1ace501fe' 
  AND token = 'd40uFp0IHQKaD6JS1YpGIlU3LaLPA6VSoSMzEEnZPvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}