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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43420832c44846ac966b4a338d047ce60e7d121867a007d1b2e8bee352dc7247' 
  AND token = 'MiSeEMeLt5bHwYoFRvWxbVJJZGSmZnqaTeX2S06/3Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}