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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a9efef1c78ec3863bb0b98c153cb5e35a63e8b9174852070c1b405204139b40' 
  AND token = '0ZjH3n+THFLw2LI0JG/0Ne/BziBd15BW4aLITjHHtZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}