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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb6be0daee98d7dc87ebb2b0a29da36d60e1d73bc8f9292e276cacff5269bc1' 
  AND token = '73tUmKKKrAkfapTY/01IDHedtAZnqgkutec5r8TRqLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}