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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8e6e17e71c2bed03e0416428edff3e936b14e44b5a24e1d518e4d14b6328af' 
  AND token = 'iuPRdgR8GO7MwE9HBeIwSv5tElO3xKuoLNN+r7qZl7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}