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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65fa7c26d35daadc60c475f16193f4b14898075b7f359922ad9022d9fc8d2b33' 
  AND token = 'Yoy1U6cLN19QNFU2avZ/9f8FCbpfF7OYzbBRMGWnq+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}