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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6129ef2d40a9803131000475ff327d2f646c1d9f30bd16cc33aa766da2e2f22a' 
  AND token = 'XGJHaTcoox6tuM5454+ktR6kYl/neGouTyF06UFN75I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}