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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4394ee250bbcb5b15b15d7d9f6c69c9831aca6dece7834d847e16b199160b1f1' 
  AND token = 'Ox9gqKyOje79Zj9WJ9rqOmrqZNLB2JytNKSvkBvk9/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}