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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4ab51e5f363a12ff28a66101138661e1bb44b6fb144462a5387da9582c9ab3' 
  AND token = 'l1V8LnP/L5SIw7t+JXf3NurFZVFewCLoEWsL7DQSMBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}