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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '651aa6d253f53a752cc786ea1e2d2759aecc0114cefe52ab5d9560c29e88017a' 
  AND token = '6LP3SI83HlRUK6EhfC17eUEKvlC+9OLaYL+WbgQfKIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}