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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61d4a83a2c748e088a3b4b8467c0d7d288c20dec6f449e1a591bb77f993c1713' 
  AND token = 'yHnZ2dUHPAyulYU77gJ65z2VXFlXV5pMzDXR7DhM4Js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}