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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8ac7f9dc2b143524f1cc94272124ad8dab223ef29dabb87159d1205f5c56d3' 
  AND token = 'WXV0EQMT7ToWKvEgV4zjYgHiPB64uyf9sXRd44wUVMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}