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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71184eaab2f33339e1b81e3b18ce75da1f5361920bf80510017c417d31a65358' 
  AND token = 'VH4ghKCNTl7dAKac+7n/iMX75WmtClggljlqx3DFOYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}