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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436f20332e86d9941d5f60e51c6c56411e5dfc26d1a92d959221e75aec4378cc' 
  AND token = '4COVy2Nr1xyxe1+4N2G0FVRIuXCG0yhbpAU6MOtOCDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}