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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff125ea1992f3f8850dc022596f6b18cc77557159e8e81e5e6d2ab8124220e2' 
  AND token = 'eCV1nuSaCK0TyUrUg1jlxt1hggAFr7dufItg5Y8+6/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}