Sandbox

SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d74d3d3a1f5802f896a89821fdc1a724d717c5f25000d5039e8a5f042df463' 
  AND token = 'ElBPvQ3GHTK7b+Fz/zmvcMAMttTjvDALSsDhDH+aua8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}