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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b74c7e7345ea627a8b7ae9d6191bd7d605450b6f8e3241b9c9fa0c595e477b06' 
  AND token = 'f7tRGtDtaXcQNyEcSv5BXB/ApKGwB2lPC/blTOYK8y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}