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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '639c5aac20f0e8242f1233d473e8e8aa6986820e67ef94d4db0acd1da741f54f' 
  AND token = 'vqhfh8Qpu/qNaFxXEfYcQH6gO/fNhVn2LrXEsOejiIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}