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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e7546978a1cf7c8a7482710ba188af4f6521fa8e54761cfb7f07f9f3f355e2' 
  AND token = 'orV/Z9iA/PrJStPmKqCJSgXg4sLcV52L+a5TfFgzHZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}