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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '017a90a60d7d6374fef93e384d0f726f3e2a6fd2bb4b2fa686d3ab80490802af' 
  AND token = 'kuS18wTn6mG1qi1EYCAoVAORCi9DMUVo2+k/yqumxaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}