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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f2b999eef4e9b70f2130b4e594e3bfe196b4d53f9b17245376b8ce4f1e0910' 
  AND token = 'stqlnqM/PK1/wOF13dFsHnMvaPC6qg2GRqfHkfqdFcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}