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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbe3b4e9f7bfb8c7571d4d05b618f689d3d2e9e03dc3505633c7cc89514c3baa' 
  AND token = 'FUViw7CFczgYAEUbi8h7kxh2XqqS4UEdf3tC+nCOQc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}