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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fcb8fa1103ee1963b5f42b902d6ea461ccbfdd4faa2e640f513019c52678f09' 
  AND token = 'QEPSbogmPO04iSFwcgYXUhHuRT7SCzPt40k07yCjuFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}