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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8929cb43b0bf3a355864d90c2d28595dc8b49b2f0fcd54fee4fd819d0d4228f' 
  AND token = 'XyBXxMqYFGPYgSqo8n6PAak7s2scihXo/zXeNtPcBcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}