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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff7a3dc9b2d820505f21575fb752767150a20f96f0bb024e2ccec3eaa18fe67' 
  AND token = 'Eu4/yZiuSgEqQE2m7kYH7NTlv+D4muBdsryjxhVbCEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}