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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39768a65459ce6491a56b54d0f2642905e259d1f7d1d0461d5abd919ca2c04a7' 
  AND token = 'l4QtmzXbgdWl7vPkSczQvtD5h+qeB0dP6JDmomlN08Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}