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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c144b1b8edf827a202425918b7c0aa3d4c1b5db70b33d49693980aa5411b2a5f' 
  AND token = 'wNxeUeH7uO0oaE+J13qT3iZkg68l+QTI1EWPt9bhzxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}