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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7b16153c17678fd0aefeed79cf07124930a3b4609b3a888db3f87fdb351c951' 
  AND token = 'T1pZ3YD7FVmM8SA7HcoFct3B+aafeSyX5IqqNo/DFUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}