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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afcd22175aaab26cbac2ccfa776eb36330109e508cdea304079c44eb57ae475c' 
  AND token = 'mA8w+g3we67Nnm1F7UBPI1Ue6YHcphM36BNiTZjbg/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}