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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c858b269e9b8b532660acc76963d2e531d1a5ecdf741b184cec19a00bc7f5886' 
  AND token = 'o9PxreNY/oH0maIwhk84+TX6ArsGtYYE8SadAAHs++k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}