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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292aef76a7568cb60be11c5eee47bdf53c16941e294646b73cbf5741eb7471a0' 
  AND token = '1wB0XpL98B+1AzKBZgHHAGDRZCeS6FfH3XJ9AY1pZAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}