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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4a85afc5adbab9bc52bdf0aaf091cd91ac5ca45712f57dc270f9c2189790241' 
  AND token = 'KsL73B28FsdbR9mAzUbsR/NkesRXfSpxAZ+1a+6Nwvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}