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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e2500c557e1b4c67e72f1d5b43a399400732259812702a0f93dd01c91fb8ac' 
  AND token = 'Zyaz1df3tz8vU+EV8lTCTn7e77MdCt13r6S+R7Xe69I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}