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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d2aa23e7e308e0fab9d5c6a33884f709dc49a1a57ce766419ab02802f41429' 
  AND token = 'RbDT8K3/TMTi3rY7LTlNSwqOreNQ/yK03TpgbPVKKlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}