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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2724ecf7e681f066d9b4eda0b36657967948876ce76050d0a876bb1052f6b5' 
  AND token = 'rO6ooZESW3PO0yjlV8JMeFLf/OGSBWUtDiMdZV6T/HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}