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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f615d494992195850e1215d41a667574d3fa6549e7ef258c2d505f50c1a17026' 
  AND token = 'ZcUHlyS5Gd/BFOVeErC8XHGp11vyO8mE+8w8CAyQnU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}