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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f0cb0df0d45983a04b5fd4649743da209dc589b806540744b69df19f766f70' 
  AND token = '537baLaO0AEuQ+v0VRK2m7A7zE1t1uAq+OPhU2J8mZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}