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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49371ac13585aec06a6014c4c4ed62966b125aa52be9488265073248ae9335fd' 
  AND token = 'nYCAFCd0tDpyh6lGQmD16y96d8gMuo3n8wItOQGaCgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}