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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5280f2f453fd6d6ee76a65c9030fac5e5488ade6850925553a4e20fe87ebc0b' 
  AND token = 'lB1FwNMXRWpOx1DzOyqLjxJ4UCn1lxdIgnLL6kP4GQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}