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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dee66bbf99d7ecf780e4cfa233fab1220abca6186f7de30188f6adc5094d1d0' 
  AND token = 'Vn54c1GjINp515G7qHPEYjK3SQl9u+Y3z2zkTothD5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}