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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40bc97e116410557e21fac23072168f126f0f2a766b49d0cb62360a49c391c6d' 
  AND token = 'DhYn78Lh/u/yuREKU2FTe8VFBQkw1rMxyQC7nle08Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}