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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de89c8b408708103158c6bc74ad86e4c898fa1f4b811e4dbe00bf444d90c485a' 
  AND token = 'Xlg3j0B5XfLfNAdRT/giqytlQx4h04TdY0lnwsPu0y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}