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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6fd0c853fc9995accccbe1d402f8cc8126272245b7dfbc528a3d399da275946' 
  AND token = 'ttrVVF3I7EIZeOUiY6qHW7KNJRNZu2w6kYvYfW5ALhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}