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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5521859801fe3bd5e1355f3fd79c5b827f73b7f1520a6f4b92ec50c09ab35770' 
  AND token = '/V9z7wYeVWBdfK5K1ozSpFDdkbp/BxaSyt3yHqbcWVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}